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| Astana – Guimarães | 1:1 (end) | | | Molde – APOEL | 0:1 (end) | | | Heidenheim – Chelsea | 0:2 (end) |
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| Fiorentina – Pafos | 3:2 (end) | | | Rapid – Shamrock | 1:1 (end) | | | Omonia Nikósie – Legia | 0:3 (end) |
| Ljubljana – Larne | 1:0 (end) | | | Lugano – Gent | 2:0 (end) | | | Mladá Boleslav – Betis | 2:1 (end) |
| Alkmaar – Galatasaray AŞ | 1:1 (end) | | | Anderlecht – Porto | 2:2 (end) | | | Bilbao – Elfsborg | 3:0 (end) |
| Beşiktaş – Maccabi Tel Aviv | 1:3 (end) | | | Dynamo Kyiv – Plzeň | 1:2 (end) | | | Qarabağ FK – Lyon | 1:4 (end) |
| Lazio – Ludogorec | 0:0 (end) | | | RFS Riga – PAOK | 0:2 (end) | | | Braga – Hoffenheim | 3:0 (end) |
| FCSB – Olympiacos | 0:0 (end) | | | Ferencváros – Malmö | 4:1 (end) | | | Man Utd. – Bodø/Glimt | 3:2 (end) |
| Midtjylland – Frankfurt | 1:2 (end) | | | Nice – Rangers | 1:4 (end) | | | Real Sociedad – Ajax | 2:0 (end) |
| Slavia – Fenerbahçe | 1:2 (end) | | | Tottenham – Roma | 2:2 (end) |
final
RSC Anderlecht 
2:2
(0:1)
FC Porto |
54
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Yellow card for team FC Porto (Francisco Moura).
|
|
|
44
|
Yellow card for team FC Porto (Nico González).
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|
|
34
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Yellow card for team FC Porto (João Mário).
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|
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29
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Yellow card for team RSC Anderlecht (Moussa N'Diaye).
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Goals:
52. Degreef (Rits), 86. Amuzu (N'Diaye) – 24. Galeno (pen.), 83. Vieira (N. González)
Ball possession: 52 % : 48 %.
Shots on target: 5:5. Shots off target: 4:4. Corners: 7:5. Offsides: 6:2. Fouls: 7:16.
Referees: M. Krogh – D. Wollenberg Rasmussen, S. Bramsen (vš. DEN)
Attendance: 17 717
Cards: 29. N'Diaye (AND) – 34. João Mário (PRT), 44. N. González (PRT), 54. Moura (PRT)
Penalty missed:
Ball possession: 52 % : 48 %.
Shots on target: 5:5. Shots off target: 4:4. Corners: 7:5. Offsides: 6:2. Fouls: 7:16.
RSC Anderlecht:
Coosemans (C) – Foket (84. Engwanda), M. Jörgensen, Simić, N'Diaye – Rits, Stroeykens, Dendoncker (84. Verschaeren) – Edozie (60. Amuzu), Dolberg (72. Vázquez), Degreef (73. Dreyer).
Subs: Kikkenborg, T. Vanhoutte – Angulo, Lapage, Leoni.
Coach: David Hubert
FC Porto: D. Costa (C) – João Mário (46. M. Fernandes), Pérez, Otávio, Moura – N. González, Eustáquio (82. Vieira), Varela – Pepê (75. Borges), Omorodion, Galeno.
Subs: Ramos – Namaso, T. Djaló, Franco, Mora, Navarro, Zé Pedro, Sousa, Sanusi.
Coach: Vitor Bruno
Subs: Kikkenborg, T. Vanhoutte – Angulo, Lapage, Leoni.
Coach: David Hubert
FC Porto: D. Costa (C) – João Mário (46. M. Fernandes), Pérez, Otávio, Moura – N. González, Eustáquio (82. Vieira), Varela – Pepê (75. Borges), Omorodion, Galeno.
Subs: Ramos – Namaso, T. Djaló, Franco, Mora, Navarro, Zé Pedro, Sousa, Sanusi.
Coach: Vitor Bruno
Referees: M. Krogh – D. Wollenberg Rasmussen, S. Bramsen (vš. DEN)
Attendance: 17 717