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| Gent – Molde | 2:1 (end) | | | Djurgården – Guimarães | 1:2 (end) | | | APOEL – Banja Luka | 0:1 (end) |
| Rapid – Noah | 1:0 (end) | | | Hearts – Omonia Nikósie | 2:0 (end) | | | Pan. Ateny – Chelsea | 1:4 (end) |
| Jagiellonia – Petrocub Hîncești | 2:0 (end) | | | Celje – Başakşehir | 5:1 (end) | | | Larne – Shamrock | 1:4 (end) |
| Betis – København | 1:1 (end) | | | Helsinki – Dinamo Minsk | 1:0 (end) | | | Ljubljana – Linec | 2:0 (end) |
| New Saints – Astana | 2:0 (end) | | | Mladá Boleslav – Lugano | 0:1 (end) | | | Bačka Topola – Legia | 0:3 (end) |
| Pafos – Heidenheim | 0:1 (end) |
| Roma – Dynamo Kyiv | 1:0 (end) | | | Ferencváros – Nice | 1:0 (end) | | | Frankfurt – RFS Riga | 1:0 (end) |
| Qarabağ FK – Ajax | 0:3 (end) | | | Maccabi Tel Aviv – Real Sociedad | 1:2 (end) | | | PAOK – Plzeň | 2:2 (end) |
| Anderlecht – Ludogorec | 2:0 (end) | | | Bilbao – Slavia | 1:0 (end) | | | Porto – Hoffenheim | 2:0 (end) |
| Fenerbahçe – Man Utd. | 1:1 (end) | | | Lyon – Beşiktaş | 0:1 (end) | | | Malmö – Olympiacos | 0:1 (end) |
| Rangers – FCSB | 4:0 (end) | | | Tottenham – Alkmaar | 1:0 (end) | | | Twente – Lazio | 0:2 (end) |
final
Real Betis 
1:1
(1:0)
FC København |
82
|
Yellow card for team FC København (Elias Achouri).
|
|
|
78
|
Yellow card for team Real Betis (Pablo Fornals).
|
|
|
77
|
Yellow card for team Real Betis (Abde Ezzalzouli).
|
|
|
37
|
Yellow card for team Real Betis (Aitor Ruibal).
|
|
|
32
|
Yellow card for team FC København (Mohamed Elyounoussi).
|
Goals:
8. Ezzalzouli (Ávila) – 77. Diks (pen.)
Ball possession: 54 % : 46 %.
Shots on target: 5:2. Shots off target: 5:2. Corners: 4:1. Offsides: 5:1. Fouls: 13:12.
Referees: Delajod – Finjean, Jeanne (FRA)
Attendance:
Cards: 37. Ruibal (RBE), 77. Ezzalzouli (RBE), 78. Fornals (RBE) – 32. Elyounoussi (KOD), 82. Achouri (KOD)
Penalty missed:
Ball possession: 54 % : 46 %.
Shots on target: 5:2. Shots off target: 5:2. Corners: 4:1. Offsides: 5:1. Fouls: 13:12.
Real Betis:
Adrián – Ruibal (62. Bellerín), Llorente, de Souza, Rodríguez – Fornals, Cardoso (81. Juanmi), Altimira, Ezzalzouli (81. Diao) – Bakambu (46. Roque), Ávila.
Subs: R. Silva, González – Bartra, Perraud, Sabaly, Mendy, Rodriguez, Flores.
Coach: : Manuel Pellegrini
FC København: Trott – Huescas, Gabriel Pereira, Chatzidiakos, Diks – Mattsson (62. Larsson), Clem (62. Delaney) – Claesson (70. Cornelius), Lerager (70. Froholdt), Robert (62. Achouri) – Elyounoussi.
Subs: Rúnarsson, Sander – Garananga, Onugcha, López, Chiakha, Höjer.
Coach: Jacob Neestrup
Subs: R. Silva, González – Bartra, Perraud, Sabaly, Mendy, Rodriguez, Flores.
Coach: : Manuel Pellegrini
FC København: Trott – Huescas, Gabriel Pereira, Chatzidiakos, Diks – Mattsson (62. Larsson), Clem (62. Delaney) – Claesson (70. Cornelius), Lerager (70. Froholdt), Robert (62. Achouri) – Elyounoussi.
Subs: Rúnarsson, Sander – Garananga, Onugcha, López, Chiakha, Höjer.
Coach: Jacob Neestrup
Referees: Delajod – Finjean, Jeanne (FRA)
Attendance: