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| Gent – Molde | 2:1 (end) | | | Djurgården – Guimarães | 1:2 (end) | | | APOEL – Banja Luka | 0:1 (end) |
| Rapid – Noah | 1:0 (end) | | | Hearts – Omonia Nikósie | 2:0 (end) | | | Pan. Ateny – Chelsea | 1:4 (end) |
| Jagiellonia – Petrocub Hîncești | 2:0 (end) | | | Celje – Başakşehir | 5:1 (end) | | | Larne – Shamrock | 1:4 (end) |
| Betis – København | 1:1 (end) | | | Helsinki – Dinamo Minsk | 1:0 (end) | | | Ljubljana – Linec | 2:0 (end) |
| New Saints – Astana | 2:0 (end) | | | Mladá Boleslav – Lugano | 0:1 (end) | | | Bačka Topola – Legia | 0:3 (end) |
| Pafos – Heidenheim | 0:1 (end) |
| Roma – Dynamo Kyiv | 1:0 (end) | | | Ferencváros – Nice | 1:0 (end) | | | Frankfurt – RFS Riga | 1:0 (end) |
| Qarabağ FK – Ajax | 0:3 (end) | | | Maccabi Tel Aviv – Real Sociedad | 1:2 (end) | | | PAOK – Plzeň | 2:2 (end) |
| Anderlecht – Ludogorec | 2:0 (end) | | | Bilbao – Slavia | 1:0 (end) | | | Porto – Hoffenheim | 2:0 (end) |
| Fenerbahçe – Man Utd. | 1:1 (end) | | | Lyon – Beşiktaş | 0:1 (end) | | | Malmö – Olympiacos | 0:1 (end) |
| Rangers – FCSB | 4:0 (end) | | | Tottenham – Alkmaar | 1:0 (end) | | | Twente – Lazio | 0:2 (end) |
final
Panathinaikos FC 
1:4
(0:1)
Chelsea FC |
90+3
|
Yellow card for team Chelsea FC (Axel Disasi).
|
|
|
58
|
Yellow card for team Panathinaikos FC (Filip Mladenović).
|
Goals:
69. Pellistri (Vagiannidis) – 23. Félix (Mudryk), 49. Mudryk (Neto), 55. Félix (Mudryk), 59. Nkunku (pen.)
Ball possession: 40 % : 60 %.
Shots on target: 3:9. Shots off target: 5:5. Corners: 5:6. Offsides: 2:1. Fouls: 8:17.
Referees: Nobre (POR) – Ribeiro (POR), Pereira (POR)
Attendance: 59 742
Cards: 58. Mladenović (PAN) – 90+3. Disasi (CHE)
Penalty missed:
Ball possession: 40 % : 60 %.
Shots on target: 3:9. Shots off target: 5:5. Corners: 5:6. Offsides: 2:1. Fouls: 8:17.
Panathinaikos FC:
Drągowski – Kotsiras, Schenkeveld (C), Jedvaj, Mladenović (60. Vagiannidis) – Gnezda Čerin, Maksimović – Mancini (60. Tetê), Ounahi (80. Bakasetas), Pellistri (70. Đuričić) – Jeremejeff (70. Šporar).
Subs: Lilo, Lodygin – Arão, Gregou, Ingason, Ntampizas, Fikaj.
Coach: Diego Alonso
Chelsea FC: Jørgensen – Veiga, Badiashile, Disasi, Cucurella – Dewsbury-Hall (77. Chukwuemeka), Fernández (C) (71. Casadei), Félix – Neto (61. Tyrique), Nkunku (61. Guiu), Mudryk.
Subs: Bergström, Robert Sánchez – Adarabioyo, Madueke, Sancho, Rak-Sakyi, Mheuka.
Coach: Enzo Maresca
Subs: Lilo, Lodygin – Arão, Gregou, Ingason, Ntampizas, Fikaj.
Coach: Diego Alonso
Chelsea FC: Jørgensen – Veiga, Badiashile, Disasi, Cucurella – Dewsbury-Hall (77. Chukwuemeka), Fernández (C) (71. Casadei), Félix – Neto (61. Tyrique), Nkunku (61. Guiu), Mudryk.
Subs: Bergström, Robert Sánchez – Adarabioyo, Madueke, Sancho, Rak-Sakyi, Mheuka.
Coach: Enzo Maresca
Referees: Nobre (POR) – Ribeiro (POR), Pereira (POR)
Attendance: 59 742