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| Ferencváros – Tottenham | 1:2 (end) | | | Hoffenheim – Dynamo Kyiv | 2:0 (end) | | | Qarabağ FK – Malmö | 1:2 (end) |
| Lazio – Nice | 4:1 (end) | | | Maccabi Tel Aviv – Midtjylland | 0:2 (end) | | | Olympiacos – Braga | 3:0 (end) |
| Real Sociedad – Anderlecht | 1:2 (end) | | | RFS Riga – Galatasaray AŞ | 2:2 (end) | | | Slavia – Ajax | 1:1 (end) |
| Bilbao – Alkmaar | 2:0 (end) | | | Beşiktaş – Frankfurt | 1:3 (end) | | | Elfsborg – Roma | 1:0 (end) |
| Porto – Man Utd. | 3:3 (end) | | | PAOK – FCSB | 0:1 (end) | | | Rangers – Lyon | 1:4 (end) |
| Twente – Fenerbahçe | 1:1 (end) | | | Plzeň – Ludogorec | 0:0 (end) |
| Dinamo Minsk – Hearts | 1:2 (end) | | | Astana – Bačka Topola | 1:0 (end) | | | Heidenheim – Ljubljana | 2:1 (end) |
| Legia – Betis | 1:0 (end) | | | Molde – Larne | 3:0 (end) | | | Noah – Mladá Boleslav | 2:0 (end) |
| Omonia Nikósie – Víkingur Reykjavík | 4:0 (end) | | | Chelsea – Gent | 4:2 (end) | | | Linec – Djurgården | 2:2 (end) |
| Lugano – Helsinki | 3:0 (end) | | | Petrocub Hîncești – Pafos | 1:4 (end) | | | Shamrock – APOEL | 1:1 (end) |
| Banja Luka – Pan. Ateny | 1:1 (end) | | | København – Jagiellonia | 1:2 (end) | | | Fiorentina – New Saints | 2:0 (end) |
final
Chelsea FC 
4:2
(1:0)
KAA Gent |
90+4
|
Yellow card for team KAA Gent (Archie Brown).
|
|
|
72
|
Yellow card for team Chelsea FC (Axel Disasi).
|
Goals:
12. Veiga (Mudryk), 46. Neto (Disasi), 63. Nkunku (Veiga), 70. Dewsbury-Hall – 50. Watanabe (Gudjohnsen), 90. Gandelman (Dean)
Ball possession: 68 % : 32 %.
Shots on target: 4:3. Shots off target: 9:4. Corners: 9:4. Offsides: 0:2. Fouls: 9:7.
Referees: Schlager – Foltyn, Waschitzki
Attendance:
Cards: 72. Disasi (CHE) – 90+4. Brown (GNT)
Penalty missed:
Ball possession: 68 % : 32 %.
Shots on target: 4:3. Shots off target: 9:4. Corners: 9:4. Offsides: 0:2. Fouls: 9:7.
Chelsea FC:
Jørgensen – Disasi, Adarabioyo, Badiashile, Veiga – Dewsbury-Hall, Casadei, Neto (80. Tyrique) – Félix, Nkunku (80. Guiu), Mudryk.
Subs: Bergström, Robert Sánchez – Caicedo, Colwill, Cucurella, Fernández, Madueke, Dyer.
Coach: Enzo Maresca
KAA Gent: Roef – Gambor (89. Samoise), Watanabe, Mitrović, Torunarigha – Ito, Delorge (78. Gandelman) – Fadiga (64. Araujo), Surdez (78. Kums), Brown – Gudjohnsen (64. Dean).
Subs: Schmidt – de Vlieger, Fortuna, Gerkens, Sonko, Vancsa, H. Varela.
Coach: Wouter Vrancken
Subs: Bergström, Robert Sánchez – Caicedo, Colwill, Cucurella, Fernández, Madueke, Dyer.
Coach: Enzo Maresca
KAA Gent: Roef – Gambor (89. Samoise), Watanabe, Mitrović, Torunarigha – Ito, Delorge (78. Gandelman) – Fadiga (64. Araujo), Surdez (78. Kums), Brown – Gudjohnsen (64. Dean).
Subs: Schmidt – de Vlieger, Fortuna, Gerkens, Sonko, Vancsa, H. Varela.
Coach: Wouter Vrancken
Referees: Schlager – Foltyn, Waschitzki
Attendance: