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| Ferencváros – Tottenham | 1:2 (end) | | | Hoffenheim – Dynamo Kyiv | 2:0 (end) | | | Qarabağ FK – Malmö | 1:2 (end) |
| Lazio – Nice | 4:1 (end) | | | Maccabi Tel Aviv – Midtjylland | 0:2 (end) | | | Olympiacos – Braga | 3:0 (end) |
| Real Sociedad – Anderlecht | 1:2 (end) | | | RFS Riga – Galatasaray AŞ | 2:2 (end) | | | Slavia – Ajax | 1:1 (end) |
| Bilbao – Alkmaar | 2:0 (end) | | | Beşiktaş – Frankfurt | 1:3 (end) | | | Elfsborg – Roma | 1:0 (end) |
| Porto – Man Utd. | 3:3 (end) | | | PAOK – FCSB | 0:1 (end) | | | Rangers – Lyon | 1:4 (end) |
| Twente – Fenerbahçe | 1:1 (end) | | | Plzeň – Ludogorec | 0:0 (end) |
| Dinamo Minsk – Hearts | 1:2 (end) | | | Astana – Bačka Topola | 1:0 (end) | | | Heidenheim – Ljubljana | 2:1 (end) |
| Legia – Betis | 1:0 (end) | | | Molde – Larne | 3:0 (end) | | | Noah – Mladá Boleslav | 2:0 (end) |
| Omonia Nikósie – Víkingur Reykjavík | 4:0 (end) | | | Chelsea – Gent | 4:2 (end) | | | Linec – Djurgården | 2:2 (end) |
| Lugano – Helsinki | 3:0 (end) | | | Petrocub Hîncești – Pafos | 1:4 (end) | | | Shamrock – APOEL | 1:1 (end) |
| Banja Luka – Panathinaikos | 1:1 (end) | | | København – Jagiellonia | 1:2 (end) | | | Fiorentina – TNS | 2:0 (end) |
final
Glasgow Rangers 
1:4
(1:3)
Olympique Lyon |
83
|
Yellow card for team Olympique Lyon (Saïd Benrahma).
|
|
|
72
|
Yellow card for team Olympique Lyon (Jordan Veretout).
|
|
|
65
|
Yellow card for team Olympique Lyon (Rayan Cherki).
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|
53
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Yellow card for team Glasgow Rangers (Connor Barron).
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24
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Yellow card for team Glasgow Rangers (John Souttar).
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Goals:
14. Lawrence (Dessers) – 10. Fofana (Cherki), 19. Lacazette (Fofana), 45+1. Lacazette (Tolisso), 55. Fofana (Cherki)
Ball possession: 50 % : 50 %.
Shots on target: 6:7. Shots off target: 5:4. Corners: 3:2. Offsides: 2:4. Fouls: 11:2.
Referees: Jablonski (GER) – Beitinger (GER), Thielert (GER)
Attendance: 41 981
Cards: 24. Souttar (RFC), 53. Barron (RFC) – 65. Cherki (LYO), 72. Veretout (LYO), 83. Benrahma (LYO)
Penalty missed:
Ball possession: 50 % : 50 %.
Shots on target: 6:7. Shots off target: 5:4. Corners: 3:2. Offsides: 2:4. Fouls: 11:2.
Glasgow Rangers:
Butland – Tavernier (C) (61. Kasanwirjo), R. Pröpper, Souttar, Jefté – Diomande, Barron (69. Raskin) – Černý (69. Sterling), Lawrence (46. Dowell), Bajrami (81. McCausland) – Dessers.
Subs: Kelly – Balogun, Igamane, King, Fraser, McKinnon, Lovelace.
Coach: Philippe Clement
Olympique Lyon: Perri – Maitland-Niles, Mata (42. Niakhaté), Ćaleta-Car, Tagliafico – Tolisso, Matić (28. Caqueret), Veretout (75. M. Diawara) – Fofana (75. Benrahma), Lacazette (C), Cherki (76. Nuamah).
Subs: Bengui, Descamps – Orban, Zaha, Abner, Kumbedi, Mikautadze.
Coach: Pierre Sage
Subs: Kelly – Balogun, Igamane, King, Fraser, McKinnon, Lovelace.
Coach: Philippe Clement
Olympique Lyon: Perri – Maitland-Niles, Mata (42. Niakhaté), Ćaleta-Car, Tagliafico – Tolisso, Matić (28. Caqueret), Veretout (75. M. Diawara) – Fofana (75. Benrahma), Lacazette (C), Cherki (76. Nuamah).
Subs: Bengui, Descamps – Orban, Zaha, Abner, Kumbedi, Mikautadze.
Coach: Pierre Sage
Referees: Jablonski (GER) – Beitinger (GER), Thielert (GER)
Attendance: 41 981